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What’s the Difference Between Blood and Serum? Blood vs. Serum!

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Key Difference: These two words are interlinked with biological science, moreover, with our human body, which is nothing but Blood and Serum. Blood is the fluid of connective tissue, whereas Serum is a liquid component of the blood. The blood contains cells and clotting factors, whereas Serum does not contain these factors. Serum contains a variety of proteins, enzymes, and hormones. Blood is composed of cells suspended in plasma. You can learn the vast differences between “Blood and Serum” in this article.

Good Examples of the words “Blood and Serum” are,
1. The genes in our body determine the blood group.
2. Blood serum transports hormones such as insulin and cortisol.



Blood is the main component of our human body.

Blood is the liquid and solid portion of the body, which is the connective tissue that helps regulate more crucial functions, and it depends on Red blood cells, which decide the colour of the Blood. It depends on the creatures. There are four types of Blood present, A, AB, B, and O. Blood determines by the presence and absence of antigens in Red blood cells, and it helps in transporting oxygen, and they contain a protein called haemoglobin, whereas White blood cells work and prevent us from infection caused by bacteria, algae, etc.,

The Best Example of Blood is, “Blood plays an essential role in our body.” 

How do We Spell the Word Blood?

The vocal representation of the word Blood is “bluhd.” Below, you can know by hearing the audio of the word Blood.


Syllabification refers to letters that hold together to make a single sound. So, for example, we will see the syllable of the word “Blood” is one “BLOOD.”

How do We Pronounce “Blood”?

“Blood” – Pronunciation

Using “Blood” in sentences:

  • The human body is made up of blood cells.
  • There are wide varieties of blood types.
  • Red blood cells and White blood cells are the primary blood cells in our body.
  • Henry is the blood relation to Smith.
  • I have high blood pressure, which leads to diseases.



Serum is a component of blood.

Serum is the yellowish clear liquid that remains after the blood cells and fibrinogen has been removed through the clotting process. Blood serum is commonly used for diagnostic tests and other analyses in medical and research settings. It regulates the thyroid hormones throughout the body to help regulate various physiological processes. It is more important in diagnostic testing, immune system function, and nutrient transport. 

The Best example of “Serum” is, “Serum contains a variety of nutrients and immunity.”

How do We Spell the Word Serum?

Spell / Pronunciation in which a word or particular language is spoken among people. The Oral representation of Serum is “seeuh·ruhm”. It would help if you practised it slowly for the outcome of a perfect spell.

In Latin, the word serum is pronounced as “say-rum.” Likewise, there are many differences in the pronunciation of the word serum in multiple languages. Below, you can know by hearing the audio of the word serum.


Syllabification is where we split the words into individual vowel sounds. A syllable should have at least one vowel in the word. We are going to see the syllable of the word serum.

  • Wondering if it has two syllables in it.
  • It can be split as “SE-RUM.”

How do We Pronounce “Serum”?

“Serum” – Pronunciation

Using “Serum” in sentences:

  • Serum is used as biomaterial.
  • Human serum is used for tissue typing and cell therapy research applications.
  • How many serums are in our blood?
  • Peptide hormones and thyroid hormones are serum hormones.
  • The serum is clear, and the water is consistent.

Similarities between Blood and Serum

The title reveals the difference between Blood and Serum. But, like, you want to know also similar things about the above two words. So come, let’s see below.

  • Blood and Serum are derived from the same source, which is the liquid component, and have the same components as proteins, electrolytes, hormones, and waste products.
  • Both play an essential role in maintaining the body’s overall health and transporting oxygen and nutrients to the body’s tissues and organs. Both can be collected similarly, such as collecting a blood sample in a vein.

Compare: BLOOD & SERUM

DEFINITIONBlood is made up of liquid
and solids, connective tissue
circulates throughout the body.
Serum is a watery liquid, that contains specific substances, such as antibodies, hormones or proteins.
SYNONYMSAncestor, Linear, Gore,
Origin, Heritage, Family,
Parentage, Descent, Genealogy.
Plasma, Elixir, Antiserum, Vaccine, Antitoxin, Antibody-containing fluid and Immunoglobulin
FUNCTIONBlood plays a vital liquid and performs
many crucial functions.
It regulates pH and water balance.
Blood helps in transporting enzymes
throughout the body.
Serum plays a major role in transporting nutrients, and waste products
It contains antibodies and other immune systems that defend against infections and diseases.
COLORRed color due to the presence
of red blood cells.
A typical yellow or straw colour is the liquid portion of the blood.
PART OFPart of the Circulatory System.It is the component of blood that comes under the circulatory system.
EXAMPLESBlood is involved in the circulatory
system in the human body.
White blood cells create the immune system and prevent infection.
Smith has low blood pressure.
Blood regulates body temperature.
Blood comprises platelets and plasma.
The doctor asked patients to take blood serum tests to check their antibodies level.
The Lab technician separated the blood cells from the serum.
The immunologist develops the serum that can prevent the virus from attacking.
The researcher discovered a new protein in the serum.
Henry usually injects the serum injection to boost up the running.

Infographic Representation


Resources & References

Resources: Cambridge Dictionary (Blood & Serum), Merriam-Webster (Blood & Serum), (Blood & Serum) 
Reference:[1], Merriam-Webster. com[2][3], Dictionary. com[4].


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